Wednesday, October 31, 2012

Man with bionic leg to climb Chicago skyscraper

In this Oct. 25, 2012 photo, Zac Vawter, fitted with an experimental "bionic" leg, is silhouetted on the Ledge at the Willis Tower in Chicago. Vawter is training for the world's tallest stair-climbing event where he'll attempt to climb 103 flights to the top of theWillis Tower using the new prosthesis. (AP Photo/Brian Kersey)

In this Oct. 25, 2012 photo, Zac Vawter, fitted with an experimental "bionic" leg, is silhouetted on the Ledge at the Willis Tower in Chicago. Vawter is training for the world's tallest stair-climbing event where he'll attempt to climb 103 flights to the top of theWillis Tower using the new prosthesis. (AP Photo/Brian Kersey)

In this Oct. 25, 2012 photo, Dr. Levi Hargrove, lead researcher for the Rehabilitation Institute of Chicago's Center for Bionic Medicine, holds an experimental "bionic" prosthetic leg at the institute. Zac Vawter, a 31-year-old software engineer who lost his right leg in a motorcycle accident, will help test the trailblazing prosthetic leg, that's controlled by his thoughts, when he attempts to climb 103 flights of stairs to the top of Chicago's Willis Tower on Sunday, Nov. 4. (AP Photo/Brian Kersey)

In this Oct. 25, 2012 photo, biomedical engineer Annie Simon, left, and research prosthetist Elizabeth Halsne fit an experimental "bionic" prosthetic leg on Zac Vawter at the Rehabilitation Institute of Chicago. After losing his right leg in a motorcycle accident, the 31-year-old software engineer signed up to become a research subject, helping test a trailblazing prosthetic leg that's controlled by his thoughts. He will put this leg to the ultimate test Sunday, Nov. 4 when he attempts to climb 103 flights of stairs to the top of Chicago's Willis Tower, one of the world?s tallest skyscrapers. (AP Photo/Brian Kersey)

In this Oct. 25, 2012 photo, Suzanne Finucane, a physical therapist assistant, right, and prothetist Robert Lipschutz, top, attach electrodes to Zac Vawter's leg as he is fitted with an experimental "bionic" leg at the Rehabilitation Institute of Chicago. After losing his right leg in a motorcycle accident, the 31-year-old software engineer signed up to become a research subject, helping test a trailblazing prosthetic leg that's controlled by his thoughts. He will put this leg to the ultimate test Sunday, Nov. 4 when he attempts to climb 103 flights of stairs to the top of Chicago's Willis Tower, one of the world?s tallest skyscrapers. (AP Photo/Brian Kersey)

In this Oct. 25, 2012 photo, Zac Vawter practices walking with an experimental "bionic" leg at the Rehabilitation Institute of Chicago. After losing his right leg in a motorcycle accident, the 31-year-old software engineer signed up to become a research subject, helping test a trailblazing prosthetic leg that's controlled by his thoughts. He will put this leg to the ultimate test Sunday, Nov. 4 when he attempts to climb 103 flights of stairs to the top of Chicago's Willis Tower, one of the world?s tallest skyscrapers. (AP Photo/Brian Kersey)

(AP) ? Zac Vawter considers himself a test pilot. After losing his right leg in a motorcycle accident, the 31-year-old software engineer signed up to become a research subject, helping to test a trailblazing prosthetic leg that's controlled by his thoughts.

He will put this groundbreaking bionic leg to the ultimate test Sunday when he attempts to climb 103 flights of stairs to the top of Chicago's Willis Tower, one of the world's tallest skyscrapers.

If all goes well, he'll make history with the bionic leg's public debut. His whirring, robotic leg will respond to electrical impulses from muscles in his hamstring. Vawter will think, "Climb stairs," and the motors, belts and chains in his leg will synchronize the movements of its ankle and knee. Vawter hopes to make it to the top in an hour, longer than it would've taken before his amputation, less time than it would take with his normal prosthetic leg ? or, as he calls it, his "dumb" leg.

A team of researchers will be cheering him on and noting the smart leg's performance. When Vawter goes home to Yelm, Wash., where he lives with his wife and two children, the experimental leg will stay behind in Chicago. Researchers will continue to refine its steering. Taking it to the market is still years away.

"Somewhere down the road, it will benefit me and I hope it will benefit a lot of other people as well," Vawter said about the research at the Rehabilitation Institute of Chicago.

Bionic ? or thought-controlled ? prosthetic arms have been available for a few years, thanks to pioneering work done at the Rehabilitation Institute. With leg amputees outnumbering people who've lost arms and hands, the Chicago researchers are focusing more on lower limbs. Safety is important. If a bionic hand fails, a person drops a glass of water. If a bionic leg fails, a person falls down stairs.

The Willis Tower climb will be the bionic leg's first test in the public eye, said lead researcher Levi Hargrove of the institute's Center for Bionic Medicine. The climb, called "SkyRise Chicago," is a fundraiser for the institute with about 2,700 people climbing. This is the first time the climb has played a role in the facility's research.

To prepare, Vawter and the scientists have spent hours adjusting the leg's movements. On one recent day, 11 electrodes placed on the skin of Vawter's thigh fed data to the bionic leg's microcomputer. The researchers turned over the "steering" to Vawter.

He kicked a soccer ball, walked around the room and climbed stairs. The researchers beamed.

Vawter likes the bionic leg. Compared to his regular prosthetic, it's more responsive and more fluid. As an engineer, he enjoys learning how the leg works.

It started with surgery in 2009. When Vawter's leg was amputated, a surgeon repositioned the residual spaghetti-like nerves that normally would carry signals to the lower leg and sewed them to new spots on his hamstring. That would allow Vawter one day to be able to use a bionic leg, even though the technology was years away.

The surgery is called "targeted muscle reinnervation" and it's like "rewiring the patient," Hargrove said. "And now when he just thinks about moving his ankle, his hamstring moves and we're able to tell the prosthesis how to move appropriately."

To one generation it sounds like "The Six Million Dollar Man," a 1970s TV show featuring a rebuilt hero. A younger generation may think of Luke Skywalker's bionic hand.

But Hargrove's inspiration came not from fiction, but from his fellow Canadian Terry Fox, who attempted a cross-country run on a regular artificial leg to raise money for cancer research in 1980.

"I've run marathons, and when you're in pain, you just think about Terry Fox who did it with a wooden leg and made it halfway across Canada before cancer returned," Hargrove said.

Experts not involved in the project say the Chicago research is on the leading edge. Most artificial legs are passive. "They're basically fancy wooden legs," said Daniel Ferris of the University of Michigan. Others have motorized or mechanical components but don't respond to the electrical impulses caused by thought.

"This is a step beyond the state of the art," Ferris said. "If they can achieve it, it's very noteworthy and suggests in the next 10 years or so there will be good commercial devices out there."

The $8 million project is funded by the U.S. Department of Defense and involves Vanderbilt University, the Massachusetts Institute of Technology, the University of Rhode Island and the University of New Brunswick.

Vawter and the Chicago researchers recently took the elevator to the 103rd floor of the Willis Tower to see the view after an afternoon of work in the lab. Hargrove and Vawter bantered in the elevator in anticipation of Sunday's event.

Hargrove: "Am I allowed to trash talk you?"

"It's fine," Vawter shot back. "I'll just defer it all to the leg that you built."

At the top, Vawter stood on a glass balcony overlooking the city. The next time he heads to the top, he and the bionic leg will take the stairs.

___

AP Medical Writer Carla K. Johnson can be reached at http://www.twitter.com/CarlaKJohnson.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2012-10-31-Bionic%20Stair-Climber/id-2433a8637fb54661baaa3289260c5f98

cesar chavez day raspberry ketone ron burgundy millennial media nit championship transcendentalism bells palsy

UBS to slash 10,000 jobs in fixed income retreat

ZURICH (Reuters) - UBS unveiled plans on Tuesday to wind down its fixed income business and fire 10,000 bankers, as it adapts to tougher capital rules that make it more difficult for investment banks to turn a profit since the financial crisis.

Zurich-based UBS will focus on its private bank and a smaller investment bank, ditching much of the trading business that ran up $50 billion in losses in the financial crisis, as well as a $2.3 billion hit, which trader Kweku Adoboli, now on trial on charges of fraud and false accounting, is accused of running up.

Chief Executive Sergio Ermotti, a former Merrill Lynch and UniCredit banker who took over after the Adoboli affair last year, is leading the three-year overhaul, which is aimed at saving 3.4 billion Swiss francs ($3.6 billion), on top of existing spending cuts of 2 billion francs.

Former investment bank co-head Carsten Kengeter will lead the isolation and winding down of its fixed-income activities that are no longer profitable as a result of tougher capital rules on riskier business introduced after the crisis.

The remaining investment bank - equities, foreign exchange trading, corporate advice, and precious metals trading - will be run by Andrea Orcel, a recent Ermotti hire from Bank of America who had co-ran the unit with Kengeter until Tuesday.

"This decision has been hard but it is necessary to create a UBS that is fit for the future," Ermotti said. "The business model we are creating will be unique in the banking industry."

The measures translate to a 15 percent staff cut, taking UBS's overall staff to 54,000, from 63,745 now, already down from a 2007 peak of 83,500 as banks have shed tens of thousands of jobs globally since the financial crisis of 2008.

Of the job cuts, 2,000 will be front-office investment banking staff, the revenue generators. About 2,500 positions will go in Switzerland, slightly more than that in the United States, and the rest in Britain, Ermotti said.

UBS stopped dozens of fixed income traders from entering its London offices on Tuesday, a source at the bank said.

Some staff turned up to work to find their employee cards no longer worked at the turnstile and were then escorted to human resources, according to various sources with knowledge of the situation.

Once at human resources, they received their personal items in a bag with a letter saying they would have two weeks paid leave, after which they were to return to pick up their redundancy package, the sources said.

A smaller investment bank will leave UBS focused on its private bank, which looks after the affairs of the wealthy. With 1.6 trillion francs in assets, it is the second-largest operation of its kind in the world after Bank of America.

UBS shares, which soared 7.3 percent on Monday in anticipation of the announcement, were up another 5 percent at 13.79 francs by 1050 GMT in exceptionally heavy trading, their highest since July 2011, compared with a 0.7 percent rise for the European bank sector index.

UBS, which took a government bailout in 2008 after more than $50 billion in mortgage losses, is effectively admitting that an attempt to crack the fixed-income big league has failed.

Deutsche Bank said on Tuesday it hopes to benefit from the UBS cuts as its investment bank delivered record third-quarter sales and trading revenue.

But some analysts said other banks might be forced to follow suit even though the UBS strategy was risky.

"While other banks like CS are still sticking to their investment banks, which do not even earn their cost of equity, UBS takes the lead in responding adequately to investors' demands," said Sarasin analyst Rainer Skierka.

Credit Suisse said last week it was also cutting more costs to boost its profits and capital but did not announce the same kind of radical restructuring as UBS. [ID:nL5E8LP122]

INVESTMENT BANK LOSSES

After settling a damaging U.S. tax probe in 2009, UBS had just started to rebuild client confidence when the $2.3 billion trading scandal surfaced in September last year.

Adoboli, who worked on the bank's London-based exchange-traded equities funds desk, has pleaded not guilty to two counts of fraud and four of false accounting.

Ermotti's overhaul comes against a backdrop of far tougher regulation on riskier securities trading activities, and represents a return to advisory roots stemming from UBS's purchase of Warburg, a British merchant bank, in 1995.

The bank aims to pay out more than 50 percent of profits to shareholders from 2015, after paying its first post-crisis dividend last year, a modest 0.10 francs a share. It has put away funds in the third quarter for an unspecified dividend this year, financial chief Tom Naratil told journalists.

The costs related to the investment banking split will also lead to a fourth-quarter and full-year loss, when taken together with charges on the bank's own debt, UBS said.

The private bank also faces challenges, with profits falling as Swiss banking secrecy is weakened by repeated demands from foreign governments determined to recoup tax on undeclared funds held in offshore accounts.

However, the unit secured 7.7 billion francs in net new money from clients in the third quarter, which represents the highest result in a third quarter - typically a slow one for the business due to summer holidays - in five years.

UBS swung to a third-quarter net loss of 2.172 billion francs, hit by the restructuring charges and 863 million francs written off the value of its own debt. Analysts in a Reuters poll had forecast a net profit of 457 million francs.

UBS is aiming to reduce risk-weighted assets to below 200 billion francs by the end of 2017, from 301 billion currently. Of this the investment bank will account for roughly 70 billion francs, less than half of what it accounts for today.

($1 = 0.9366 Swiss francs)

(Additional reporting by Philipp Halstrick, Anjuli Davies, Helene Durand and Spencer Anderson; Editing by Emma Thomasson, Will Waterman and Giles Elgood)

Source: http://news.yahoo.com/ubs-slash-10-000-jobs-fixed-income-exit-054642079--sector.html

rough riders joy division norco rand paul detained asexual

Monday, October 29, 2012

Player NPCs

Spelheim: The First Magewar

In a realm of magic, war rages. Will the continent be consumed by strife, or will the people unite against the evil lurking beyond the horizon?

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?Spelheim: The First Magewar?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
NPCs

Please post any player-made NPCs in this thread. This is completely optional.

Currently recruiting players for a large-scale medieval fantasy roleplay. Please take a look.
User avatar
Seirei
Member for 2 years



Post a reply

RolePlayGateway is a site built by a couple roleplayers who wanted to give a little something back to the roleplay community. The site has no intention of earning any profit, and is paid for out of their own pockets.

If you appreciate what they do, feel free to donate your spare change to help feed them on the weekends. After selecting the amount you want to donate from the menu, you can continue by clicking on PayPal logo.

Who is online

Registered users: 106.Whit(;, Acid Trip*, Addrinvan, AdellRazh*, AdmireAtStuff*, Adoration, AiraValkov*, Aisl, Akionakamura, Alexa [Bot], AlexAlonez*, ali_rox96*, almostinsane*, alwaystheunlucky*, an0nymous*, AngelJoyeuse, Angel's Whisper, AntleredRabbit, ArhaHitomi888*, arpiainen, Asper, Astoria, AugustArria*, BBClock*, BlackDove, BleedingLover, BlueTeddyBearMelody*, BOO!, Brock10, Bromander Shepard, Bug, Carlos_Joaquin*, ceh12*, Celaira*, ChaosxChild13, Child of the Winged*, ChristyLovesYou*, chrono*, Cloasse*, cmpuncle*, ColeMaibara, Colonel_Masters*, Constellations, Cooper*, coricidinForte, cosmopolitanlove*, Crazy4Wolves99*, CrockTheKing*, Crooked Thoughts*, CussingChild, CuteAsKaylah, DarkCookie97, DarknessUndying, Darksin757*, DarlingRapture*, Deallo*, delfiler*, demented-tiger*, DemiKara*, DemonDante*, desire99600, Digital_Muse*, digs, Disarmhxc*, DreamerOnTheStars*, DustAndEchoes*, ebon15*, Erik7622*, Essence, EverFidelis, FamishedPants*, Fated*, Fateless*, Flexar*, Forget~Me~Not*, freakofnature*, Frozen Soul*, gabriellaluvscanada, Gamer_Templar*, Geekly*, Gintoki Sakata, Google [Bot], Google Adsense [Bot], Google Feedfetcher, Green~Apple, Gypsy*, Hallowed777*, Hazezon, Heather1205*, HitoriRaven*, holothewisewolf*, Holy|Orders*, Horseygirl*, IAmAlien, iCat*, iseeyou19, jackrules158*, Jadebud98, JEDH3*, Jehanne*, Jewliet115*, Kaida*, kexia*, Kobra, Kohananinja*, Korrye, krumbla*, Kuroe, Lady_Blood92243, LeagueOfI*, Lenyx*, Leon21, Lifecharacter*, lightningpoint*, LitaKnix*, Lufia, Luna Delta*, LunaSpirit*, Majestic-12 [Bot], MaliceInWonderland, Marcus*, marksmanoftruth, Mathew Littlepaw*, Mela, Merchant, Midnightclub*, minibear*, Mituna, Modesty, Morgan, MSN [Bot], MSNbot Media, mummydove, NethanielShade, Nevan, Nevermore90, nightwolf, Nikolai*, noonshine*, NorthernSoul, peace_love_dance*, PeaceEntropy&Unity*, Peaches-N-Cream*, Penfold, pieluver, Plantium*, Pride*, Princess Awinita*, psbot [Picsearch], Qaida, qbsuperstar03*, Quamei*, QueenJen*, Quitelovely487*, raindrops_autumn*, Riverstyx777, Romaneck, Rulke*, RydeDawg*, S1mon*, Saika*, Saint Crash, SarcasticMeltdown, Script*, Seanhiruki*, ShadowsoftheNine*, ShadtheWerepire, Shaodow, Shiva*, SilentMusician, Skwidge*, slcam*, SlightlyInsane*, Snow*, Solaron*, Sorella, St. Valentine, Stella11, Stilts, SuperSmash*, supertoastgirl, Sweet Angel Jocelyn*, Taidine*, Talisman, TemplarWarden*, Terrus*, The Great Thundorz*, The Keywork*, The Painkiller*, The*Lucky*Teacup, TheFirstFist, TheFlag*, TheMysticKnight, TheNoremac42*, Thorait*, Thundera*, Thundergod1020*, tigerking1292*, Tiko*, Toffeeebot*, tornadofan2*, trakira, TRUE-ASSASSIN*, Tsukiakari, TurtleSoup, UniqueYetUnoriginal, Valor*, VengefulCanary, Vestiline*, VindicatedPurpose*, Winds Of Fate*, Witless, wolfoftheage*, Wudgeous, X64*, Xiiver*, xoxMissClairexox, xXChocobeanXx, XxEvil1xX, Yahoo [Bot], Zenia*, zeno3111, zolarix*

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/tIOyPytxm7E/viewtopic.php

st. patrick s day brandon lloyd brandon lloyd celtic thunder fabrice muamba collapse prometheus trailer patrice oneal

Friday, October 26, 2012

Revenue With Reseller Web Hosting | Healthuse - Health & Fitness ...

The good results powering Internet marketing Corporation

?Online Online marketing is thought to be wide in scopes?. Internet marketing, or Website marketing, makes it possible for you to endorse your solutions and products and services web at cheaper value than standard promoting. It can help you expand your company basically because it offers professional prospects from would-be consumers who?re hunting for your goods and expert services. Businessman getting granted a 24 hour on a daily basis is regarded pressured for his give good results and process dedication. Technological innovation evolves all moment as a result of the good intellect of human. Thats why just about every load of unique obligation is dwindling as a result of it.

Placing up a company all on your own is among the most beneficial technique to endure. The very fact that you just dont ought to awaken earlier in order to take care of your self to the lengthy day forward and for that transportation time as well as the trouble of performing a great deal paper functions in the company. Obtaining unique enterprise is in addition an opening prospect for any shut doorway to progress your job. Although not all of us can manage the stress of functioning small business on our very own. Website Promotion merchants at the moment are escalating in figures due to their performance in getting your small business towards summit. Each individual great starts off by having a smaller just one, in link with this particular, your minor enterprise can develop into a gigantic just one when you be part of and encourage your merchandise and products as a result of internet marketing. Along with the benefit of dependable and notable world-wide-web advertising online businesses much larger possibilities may very well be disclosed that are hiding earlier than. Internet marketing tactics for smaller business venture are related most specially when you?re on the starting up chapter. Advices and strategies of internet marketing industry professionals make what you are promoting attractive. It wouldnt be pornographique so that you can receive moolah and get accomplishment and being successful. The vast majority of the practices they perform tend to be more skilled, enabling the consumers to discover the results of their attempts. Advertising and marketing on the web will likely be favorable seeing that all you?ll need to complete is simply open up your world-wide-web browser, make statements regarding your products then publish it. 1,000,000 of folks across the planet will capable to witness and fully understand the advantages of your services to their lives. Ad doesnt want to be incredibly quite expensive and unpleasant thanks to the technologies rewards it delivers. The most suitable world-wide-web online marketing gives effective and powerful advertising towards your merchandise. An area internet marketing services is dynamic considering most costumers convert on the Web to search for exactly what the abilities of goods are. It is perfect for many firms that want to use a neighborhood viewers. The expansion of nearest internet marketing assistance is enormous considering that it could assist with very affordable deals built to get your company to the map also, the incontrovertible fact that it can help smallish even the big internet business to perform results and triumph.

If you need to become one in every of these prosperous individuals developing a mark in internet marketing business market due to Internet marketing, you could possibly phone at +1 903.805.0408 or head to their online site.

For more info on Tutorial To Reseller And Website Hosting: Cheap Internet Internet Hosting Or Dependable Web Hosting?, in your free time please check out Internet Hosting Necessities.

Source: http://www.healthuse.com/revenue-with-reseller-web-hosting.html

google maps 8 bit mirror mirror robyn texas relays meniscus the colony kids choice awards

Thursday, October 25, 2012

Access Hollywood section

Sorry, Readability was unable to parse this page for content.

Source: http://today.msnbc.msn.com/id/7358550/ns/today-entertainment/

kourtney kardashian pregnant chip kelly billy cundiff super bowl tickets superbowl birmingham news lee evans

The TRUTH About Motherhood Autumn Pasquale, Dante Robinson ...

?

Autumn pasquale, Justin Robinson, Dante Robinson

Two teenage brothers, Justin,15, and Dante, 17,? Robinson, have been charged with allegedly murdering of 12-year-old, Autumn Pasquale, who disappeared while riding her BMX bike. After a 48-hour search for Autumn Pasquale, investigators found her body stuffed into a recycling bin behind a vacant house next to the one where the boys lived with their family. These sociopaths beat her, strangled her and stuffed her into the bin like a piece of garbage. This was someone?s little girl.

A tip from the boys? mother is what led police to the little girl?s body. She contacted the authorities when she was alarmed by one of the boy?s Facebook postings. It?s not been released what exactly the post was but it must have been outrageous to cause a mother to turn her own children in. Can you imagine how hard that must have been?

When crime scene investigators went through the family?s home, they found Autumn Pasquale ?s BMX bike, her backpack and other belongings.

Several people in Autumn Pasquale?s small hometown of Clayton, New Jersey said they saw both boys at the vigil held Monday night for Autumn. They had the balls to stand among her friends and family and al the people who were praying for her safe return, all the while knowing that she was never coming home because she was dead. Autumn was in the recycling bin, because those little sick fucks put her there.

Justin Robinson lured her to their house with the promise of trading BMX parts, where Justin and Dante Robinson strangled a little girl for her bike, stole her from all the people who loved her and then they tossed her out trash.

Autumn Pasquale, Justin Robinson, Dante Robinson

Both boys turned themselves in Tuesday and have been charged with first-degree murder, conspiracy to commit murder, disposing of a body, tampering with evidence and theft. The younger boy is also charged with luring.

The brothers, who are 15 and 17, are charged as juveniles. But Prosecutor Sean Dalton said it?s likely he?ll ask that their case be moved to adult court.

As the mother of little girls, I can?t imagine what her parents are going through. I?d imagine they are beside themselves with grief and anger. The mother of the boys, my heart breaks for her because it could not have been an easy choice to turn her sons in but she did what was right. This case has left two families broken and one little girl dead.

These boys are monsters and need to be locked away from society. They are obviously dangerous if they can be so cold and commit such a heinous crime at such a young age with no remorse and have the gall to not only throw Autumn Pasquale in the garbage but to attend her vigil and look her parents in the eyes knowing what they did. They are deviants. A throat punch is too good for these boys.

My heart goes out to their mother and the parents of Autumn Pasquale.

Comments

comments

Powered by Facebook Comments

About the author: Deborah Cruz View all posts by Deborah Cruz

Deborah Cruz, aka Truthful Mommy, is a wife, writer, semi-crunchy Ninja Mommy, tech junkie and shoe whore. "Are you there Louboutin, it's me,Debi?" Spends her days in suburbia drinking coffee, shuttling kids and planning social media world domination.


Twitter - Facebook

Source: http://www.motherhoodthetruth.com/autumn-pasquale-murdered-dante-justin-robinson/

golden globe winners 2012 ricky gervais golden globes epidermolysis bullosa miss wisconsin law abiding citizen golden globes 2012 miss america

Gene mutation identifies colorectal cancer patients who live longer with aspirin therapy

Gene mutation identifies colorectal cancer patients who live longer with aspirin therapy [ Back to EurekAlert! ] Public release date: 24-Oct-2012
[ | E-mail | Share Share ]

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-5665
Dana-Farber Cancer Institute

BOSTONAspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation, Dana-Farber Cancer Institute scientists report in the Oct. 25 issue of the New England Journal of Medicine.

In a study involving more than 900 patients with colorectal cancer, the researchers found that, for patients whose tumors harbored a mutation in the gene PIK3CA, aspirin use produced a sharp jump in survival: five years after diagnosis, 97 percent of those taking aspirin were still alive, compared to 74 percent of those not using aspirin. By contrast, aspirin had no impact on five-year survival rates among patients without a PIK3CA mutation.

"Our results suggest that aspirin can be particularly effective in prolonging survival among patients whose colorectal cancer tests positive for a mutation in PIK3CA," said the study's senior author, Shuji Ogino, MD, PhD, of Dana-Farber, Brigham and Women's Hospital, and the Harvard School of Public Health. "For the first time, we have a genetic marker that can help doctors determine which colorectal cancers are likely to respond to a particular therapy." He cautions that the results need to be replicated by other researchers before they can be considered definitive.

While aspirin is often prescribed for colorectal cancer patients, doctors haven't been able to predict which patients will actually benefit from the treatment. The new finding suggests that the survival benefit is limited to the 20 percent whose tumors have the PIK3CA mutation.

For the remaining patients, aspirin may still be used, but it is likely to be much less effective and can sometimes lead to gastrointestinal ulcers and stomach bleeding.

The study was prompted by previous research that suggested that aspirin blocks an enzyme called PTGS2 (cyclooxygenase-2), causing a slowdown in the signaling activity of another enzyme, PI3K. That led researchers to hypothesize that aspirin could be especially effective against colorectal cancers in which the PIK3CA gene which provides a subunit of PI3K is mutated.

To conduct the study, investigators obtained data on 964 patients with rectal or colon cancer from the Nurses' Health Study and the Health Professionals Follow-up Study long-term tracking studies of the health of tens of thousands of people. The data included information on the patients' use of aspirin after diagnosis and the presence or absence of PIK3CA mutations in their tumor tissue.

The study, which combines the study of disease-related genes and research into large populations of individuals, represents a new, hybrid field which Ogino has termed molecular pathology epidemiology. "The field may help us bring together information from two frontiers of cancer research at both the molecular and population levels in ways that are beneficial to patients," he said.

###

The study was supported in part by grants from the National Institutes of Health (P01 CA87969, P01 CA55075, P50 CA127003, R01 CA149222, R01 CA137178, and R01 CA151993); the Bennett Family Fund for Targeted Therapies Research; the Entertainment Industry Foundation through the National Colorectal Cancer Research Alliance; the Frank Knox Memorial Fellowship at Harvard University; and a Damon Runyon Clinical Investigator Award.

The lead author of the study is Xiaoyun Liao, MD, PhD, of Dana-Farber. In addition to Ogino, the paper's other corresponding author is Andrew Chan, MD, MPH, of Brigham and Women's and Massachusetts General Hospital. Co-authors include Paul Lochhead, MB, ChB, Reiko Nishihara, PhD, Aya Kuchiba, PhD, Mai Yamauchi, PhD, Yu Imamura, MD, PhD, Zhi Rong Qian, MD, PhD, Ruifang Sun, and Jeffrey Meyerhardt, MD, MPH, of Dana-Farber; Charles Fuchs, MD, MPH, of Dana-Farber and Brigham and Women's Hospital; Edward Giovannucci, MD, MPH, of the Harvard School of Public Health and Brigham and Women's; Teppei Morikawa, MD, PhD, of University of Tokyo Hospital; Yoshifumi Baba, MD, PhD, of Kumamoto University, Japan; Kaori Shima, DDS, PhD, of Kagoshima University, Japan; and Katsuhiko Nosho, MD, PhD, of Sapporo Medical University, Japan.

Dana-Farber Cancer Institute is a principal teaching affiliate of the Harvard Medical School and is among the leading cancer research and care centers in the United States. It is a founding member of the Dana-Farber/Harvard Cancer Center (DF/HCC), designated a comprehensive cancer center by the National Cancer Institute. It provides adult care with Brigham and Women's Hospital as Dana-Farber/Brigham and Women's Cancer Center, and it provides pediatric care with Boston Children's Hospital as Dana-Farber/Children's Hospital Cancer Center. Dana-Farber is the top-ranked cancer center in New England, according to U.S. News & World Report, and one of the largest recipients among independent hospitals of National Cancer Institute and National Institutes of Health grant funding. Follow Dana-Farber on Twitter: @dana-farber or Facebook: facebook.com/danafarbercancerinstitute.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Gene mutation identifies colorectal cancer patients who live longer with aspirin therapy [ Back to EurekAlert! ] Public release date: 24-Oct-2012
[ | E-mail | Share Share ]

Contact: Anne Doerr
anne_doerr@dfci.harvard.edu
617-632-5665
Dana-Farber Cancer Institute

BOSTONAspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation, Dana-Farber Cancer Institute scientists report in the Oct. 25 issue of the New England Journal of Medicine.

In a study involving more than 900 patients with colorectal cancer, the researchers found that, for patients whose tumors harbored a mutation in the gene PIK3CA, aspirin use produced a sharp jump in survival: five years after diagnosis, 97 percent of those taking aspirin were still alive, compared to 74 percent of those not using aspirin. By contrast, aspirin had no impact on five-year survival rates among patients without a PIK3CA mutation.

"Our results suggest that aspirin can be particularly effective in prolonging survival among patients whose colorectal cancer tests positive for a mutation in PIK3CA," said the study's senior author, Shuji Ogino, MD, PhD, of Dana-Farber, Brigham and Women's Hospital, and the Harvard School of Public Health. "For the first time, we have a genetic marker that can help doctors determine which colorectal cancers are likely to respond to a particular therapy." He cautions that the results need to be replicated by other researchers before they can be considered definitive.

While aspirin is often prescribed for colorectal cancer patients, doctors haven't been able to predict which patients will actually benefit from the treatment. The new finding suggests that the survival benefit is limited to the 20 percent whose tumors have the PIK3CA mutation.

For the remaining patients, aspirin may still be used, but it is likely to be much less effective and can sometimes lead to gastrointestinal ulcers and stomach bleeding.

The study was prompted by previous research that suggested that aspirin blocks an enzyme called PTGS2 (cyclooxygenase-2), causing a slowdown in the signaling activity of another enzyme, PI3K. That led researchers to hypothesize that aspirin could be especially effective against colorectal cancers in which the PIK3CA gene which provides a subunit of PI3K is mutated.

To conduct the study, investigators obtained data on 964 patients with rectal or colon cancer from the Nurses' Health Study and the Health Professionals Follow-up Study long-term tracking studies of the health of tens of thousands of people. The data included information on the patients' use of aspirin after diagnosis and the presence or absence of PIK3CA mutations in their tumor tissue.

The study, which combines the study of disease-related genes and research into large populations of individuals, represents a new, hybrid field which Ogino has termed molecular pathology epidemiology. "The field may help us bring together information from two frontiers of cancer research at both the molecular and population levels in ways that are beneficial to patients," he said.

###

The study was supported in part by grants from the National Institutes of Health (P01 CA87969, P01 CA55075, P50 CA127003, R01 CA149222, R01 CA137178, and R01 CA151993); the Bennett Family Fund for Targeted Therapies Research; the Entertainment Industry Foundation through the National Colorectal Cancer Research Alliance; the Frank Knox Memorial Fellowship at Harvard University; and a Damon Runyon Clinical Investigator Award.

The lead author of the study is Xiaoyun Liao, MD, PhD, of Dana-Farber. In addition to Ogino, the paper's other corresponding author is Andrew Chan, MD, MPH, of Brigham and Women's and Massachusetts General Hospital. Co-authors include Paul Lochhead, MB, ChB, Reiko Nishihara, PhD, Aya Kuchiba, PhD, Mai Yamauchi, PhD, Yu Imamura, MD, PhD, Zhi Rong Qian, MD, PhD, Ruifang Sun, and Jeffrey Meyerhardt, MD, MPH, of Dana-Farber; Charles Fuchs, MD, MPH, of Dana-Farber and Brigham and Women's Hospital; Edward Giovannucci, MD, MPH, of the Harvard School of Public Health and Brigham and Women's; Teppei Morikawa, MD, PhD, of University of Tokyo Hospital; Yoshifumi Baba, MD, PhD, of Kumamoto University, Japan; Kaori Shima, DDS, PhD, of Kagoshima University, Japan; and Katsuhiko Nosho, MD, PhD, of Sapporo Medical University, Japan.

Dana-Farber Cancer Institute is a principal teaching affiliate of the Harvard Medical School and is among the leading cancer research and care centers in the United States. It is a founding member of the Dana-Farber/Harvard Cancer Center (DF/HCC), designated a comprehensive cancer center by the National Cancer Institute. It provides adult care with Brigham and Women's Hospital as Dana-Farber/Brigham and Women's Cancer Center, and it provides pediatric care with Boston Children's Hospital as Dana-Farber/Children's Hospital Cancer Center. Dana-Farber is the top-ranked cancer center in New England, according to U.S. News & World Report, and one of the largest recipients among independent hospitals of National Cancer Institute and National Institutes of Health grant funding. Follow Dana-Farber on Twitter: @dana-farber or Facebook: facebook.com/danafarbercancerinstitute.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-10/dci-gmi102212.php

all star game oscar red carpet daytona 500 start time ryan zimmerman oscars red carpet jennifer lopez wardrobe malfunction hugo

Chinese Rare Earths Producer Suspends Output

America exports the worlds supply of helium, hasnt produced a millilitre more for over 2 decades, and keeps the price artificially low.

OPEC sets quotas and prices for global oil supplies, and can suspend or restrict production whenever they feel the need.

American agricultural conglomerates like ADM and General Mills collude to set the price at which they will accept corn from farmers. too much corn does not drive the price of it down, instead its maintained by dumping cheap corn as an export, or siloing it for next year.

how has china in any way changed how capitalism has worked for the past 270 years? The only thing thats generated outrage is chinas willingness to take an aggressively competitive position in the global economy, instead of a subservient one. If you dont like it, consider pushing for more organized labor.

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/bgeUkD_CpBQ/chinese-rare-earths-producer-suspends-output

emma roberts north korea news north korea news giuliana and bill giuliana and bill bill rancic nflx

Video reveals how ultra 3D vision helps crow grab grub

For youtube videos, paste embed code directly in the text box

-

Members do not need to provide an address

-

Rate Article

  • 1
  • 2
  • 3
  • 4
  • 5
Total votes: 0 Select Comment Validation Method
Member
Name/URL (Guest)
FaceBook (Guest) Member Commenting:


Authenticate with Facebook before submitting

OR


Make your LabSpaces comments count. Start earning LabSpaces points by becoming a member! Learn more. Please verify that you are human: Register for LabSpaces
Make your LabSpaces comments count. Start earning LabSpaces points by becoming a member! Learn more.

Please authenticate before trying to post a comment.

If you would like to remain anonymous, please enter a new name and link below


Friends

Source: http://www.labspaces.net/124812/Video_reveals_how_ultra__D_vision_helps_crow_grab_grub

leprechaun night at the museum pope shenouda bolton muamba crystal cathedral sxsw st. patrick s day

Business Ideas for the Entrepreneur with just a Laptop | Technology ...

Settling on a career in today?s turbulent global economy can seem like a shaky proposition. Fortunately, the ability to choose adaptability and flexibility means that someone with the proper motivation can not only succeed but also thrive. All you need is a laptop and the Internet.

The Ideal Workstation

Laptops are ideal for most businesses. For the active entrepreneur, especially, they are indispensable; laptops can offer the conveniences of portability, personalization, and security and their ever-increasing power means that they are able to dependably handle the tasks of nearly any software package the business may require. With a laptop, you can work at your desk, take your work with you to share at a meeting with a client, and then go over the results from the comfort of your couch. The freedom to work from anywhere means the freedom to make better business decisions and to work in whatever environment is best at the time.

Laptop Businesses

In addition to the growing number of opportunities for paid employees working from home, there are literally thousands of businesses that you can start yourself. The following are all excellent examples of how you can start a business with just your laptop:

Graphic design

Graphic designers are related to copywriters except their medium is the world of visuals. By combining text, images, and graphics, they create a unified presentation of information that their target audience can easily identify and remember. There are many opportunities within the field of graphic design, from digital motion graphics to printed material. The portability of the laptop is perfect for both creating images on the go as well as impressing a client with a portfolio presentation.

Copywriters / content creation

Copywriters write the text, or copy, for marketers and advertisers. Their goal is to write persuasively so that their audience is convinced to purchase the advertised item or to share in a specific viewpoint. The market for such copy is enormous and is not limited to the Internet itself. In addition to content for web sites, copywriters help create direct mail items, radio and television scripts, press releases, and even lyrics for songs written for commercials.

Affiliate marketing

Affiliate Marketers work with organic search engine optimization (SEO) and search engine, or pay per click marketing. They earn revenue by directing visitors, customers, and subscribers to web-based businesses such as e-retailers. There are no official requirements to begin a new affiliate marketing business but it does take the ability to act proactively and to think outside of the box in order to pursue new marketing opportunities.

Tax services

Tax preparers help other businesses and individuals prepare their often complicated tax forms and returns. To accomplish this, they utilize software programs and online services. Many governments practically require an Internet connection in order to access many of their features. Most tax preparation professionals must now have certain certifications and licensing, but nearly all requirements can be earned right from the home office. Tax preparers often find that clients appreciate the convenience and the personal attention offered by someone willing to travel to them.

Web development

Web developers continuously hone their skills. They learn from many areas: Programming languages, database building, and graphic design are but a few. Fortunately, online courses, tutorials, and web development articles are widely available. Since becoming a web developer takes no formal training, there is complete freedom in both learning and later completing the work.
Regardless of the particular profession, those that are starting their own businesses must make wise investments for their future success. The ability to work wherever one goes is a virtual requirement for getting ahead in today?s working climate, and there is simply no better tool than the laptop.

David Malmborg works with Dell. He loves all technology and right now is particularly interested in laptops and the mobile work force. You can learn more about laptops by visiting Dell.com. When not working he enjoys hiking, biking and writing about technology.

PS: Did you like this post? If so, be sure to leave a comment below.

About Jakk: Jakk Ogden is a professional self-employed blogger and the founder / owner of Technology Blogged. 22, with a love for good writing, you'll find me playing 'Drag Racing' on my HTC One X and rocking a pair of Grado headphones. If you love technology, be sure to subscribe to my feed for unique editorials. Find me on Google+. View author profile.

Source: http://www.technologyblogged.com/business-technology/business-ideas-for-the-entrepreneur-with-just-a-laptop

demi moore hospitalized james farentino somali pirates navy seals navy seal team 6 tim gunn tim gunn

Broken Plugs, Air Fresheners, and Smartphone Addiction

Readers offer their best tips for Fixing plugs that break off in their sockets, making air fresheners smell less like chemicals, and constantly checking your phone.

Don't like the gallery layout? Click here to view everything on one page.

Every day we receive boatloads of great reader tips in our inbox, but for various reasons?maybe they're a bit too niche, maybe we couldn't find a good way to present it, or maybe we just couldn't fit it in?the tip didn't make the front page. From the Tips Box is where we round up some of our favorites for your buffet-style consumption. Got a tip of your own to share? Add it in the comments, email it to tips at lifehacker.com, or share it on our tips and expert pages.

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/OmMIt3Mqkzc/

hanley ramirez Christian Bale visits victims Perez Hilton national weather service kristen stewart Christian Bale Sherman Hemsley

Ex-Goldman director Gupta awaits sentence in insider case

NEW YORK (Reuters) - The sentencing on Wednesday of fallen Wall Street titan Rajat Gupta for insider trading could come down to whether a judge agrees that his lifetime of charity counts against sending him to prison.

The former Goldman Sachs Group Inc board member was convicted in June of leaking boardroom secrets to hedge fund manager Raj Rajaratnam, his friend and former business associate, at the height of the financial crisis.

Gupta, 63, is to be sentenced by Manhattan U.S. District Judge Jed Rakoff, who oversaw the four-week trial. The former Goldman director, who also once ran the McKinsey & Co consulting firm and sat on the boards of Procter & Gamble Co and American Airlines, is the most influential corporate figure to be convicted in the recent crackdown on insider trading.

Indian-born Gupta had moved in elite business and philanthropic circles for decades until he became ensnared in the Rajaratnam case.

Gupta's lawyers have requested that he be spared prison, citing his work with groups such as the Bill & Melinda Gates Foundation on fighting disease in developing countries. Bill Gates, Microsoft Corp's co-founder, and former United Nations Secretary-General Kofi Annan are among the luminaries who have urged Rakoff to be lenient.

As one alternative to prison, the defence proposed "a less orthodox" plan in which Gupta would live and work with Rwandan government officials to help fight HIV/AIDS and malaria in rural districts, court papers said.

Federal prosecutors, however, argue that Gupta should serve eight to 10 years in prison. Gupta repeatedly flouted the law and abused his position as a corporate board member, they said.

SHAKESPEAREAN OVERTONES

Legal experts say Rakoff is unlikely to grant Gupta's request to avoid prison. The leaks of sensitive information at the heart of his case involved serious breaches of trust, said JaneAnne Murray, a white-collar defence attorney and professor at the University of Minnesota Law School.

"Balanced against that will be the breadth of his philanthropy," she said. "These extremes give this sentencing Shakespearean overtones."

Rakoff is considered by many defence attorneys to be less harsh in sentencing than some of his peers, but he has imposed significant prison terms in other insider-trading cases.

In 2011, for example, Rakoff sentenced technology consultant Winifred Jiau to four years in prison on similar insider-trading charges. Another judge sentenced Rajaratnam, who was convicted of securities fraud and conspiracy in May 2011, to 11 years.

Gupta was found guilty of three counts of securities fraud and one count of conspiracy. The maximum sentence is 20 years for securities fraud and five years for conspiracy.

He was cleared of divulging P&G's quarterly earnings in January 2009. He was also found not guilty of illegally telling Rajaratnam about Goldman's quarterly earnings after a March 12, 2007, board meeting.

Part of the prosecution's evidence was that within a minute of disconnecting from a September 2008 board call approving a $5 billion (3 billion pounds) investment in Goldman by Warren Buffett's Berkshire Hathaway Inc, Gupta called Rajaratnam. Rajaratnam then hurriedly ordered his traders to buy as much as $40 million in Goldman stock, prosecutors said.

The case is USA v Gupta, U.S. District Court for the Southern District of New York, No. 11-cr-907.

(Reporting by Basil Katz; Editing by Martha Graybow and Matthew Lewis)

Source: http://news.yahoo.com/ex-goldman-director-gupta-awaits-sentence-insider-case-040801613--finance.html

nhl playoffs masters 2012 masters the borgias shroud of turin warren sapp the masters

Wednesday, October 24, 2012

Product Review: JVC DLA-RS2 | Exact Article

If you really find this article helpful Give it a PLUS from below and help us to spread it.

If you are seeking for the finest video projectors around, you should consider the JVC. Far more specifically, try JVCs DLA-RS2. This is a single of the best projectors on the industry at the moment. If you are searching for a top quality projector at an reasonably priced value, choose the JVC DLA-RS2.

These days, a lot of folks are searching to invest in property theater systems. There is nothing at all like coming property everyday and getting able to watch your preferred film on a top quality screen that is projected from a top quality projector. Shopping for house theater accessories is extremely simple. For a house theater, most people appear for screens, projectors, speakers, and of course, motion pictures.

Exactly where can you buy this projector? Its straightforward. All you have to do is go to and you will be capable to browse JVC items.

The DLA-RS2 is the greatest projector you will find. The DLA-RS2 utilizes technology named liquid crystal on silicon. This is also employed in Sony displays. This item is absolutely a single to contemplate if youre seeking for a projector that displays a clean, crisp picture on any screen.

The product is capable to show off its 1080p D-ILA that is in a position to produce a 30,000:1 contract ratio. All of this can be accomplished with a variable iris. Doubling JVCs DLA-RS1 previous native contrast ratio, the DLA-RS2 is most certainly the greatest projector for any residence theater. This particular projector is made with a fourth-generation chip that offers its 30,000:1 on and off contrast ratio. Without having an iris, the projector is able to play films with a clear image that is positive to blow you away.

The DLA-RS2 also focuses on color accuracy. The projector is capable to show brilliant skin tones, the ideal tint of green grass, and the brilliant blue sky, all while watching a movie. The color will look so real, it will really feel like youre truly there.

For more, please go to: look into led headlights

Source: http://www.exactarticle.com/product-review-jvc-dla-rs2.htm

staten island chuck dr jekyll and mr hyde edwin jackson punksatony phil trump 2012 groundhog day groundhog phil

MLK Accident Involved Member of Mayor's Security Detail

A police officer was transported to the hospital with minor cuts and bruises after an accident during Tuesday morning's commute.

Police say the officer is a part of Mayor Michael Nutter's security detail.

The two-car accident happened on Martin Luther King Jr. Drive and Montgomery Drive around 7:45 a.m.

The officer was taken to Hahnemann Hospital where he is in stable condition.

A second person was also transported to the hospital with minor injuries. That person was in the second car involved in the accident, according to police.

The ramp from I-76 EB to Montgomery Drive and MLK Drive was closed for almost two hours.

Source: http://www.msnbc.msn.com/id/49516995/ns/local_news-philadelphia_pa/

pro bowl pro bowl 2012 rick santorum daughter gainesville 2012 royal rumble the grey machine gun kelly

New Office Web Apps get finalized for SkyDrive, Outlook

New Office Web Apps go live on SkyDrive, Outlook

As polished and functional as something might be in its preview days, a piece of work isn't done until it is done, and Microsoft's Office Web Apps have finally reached that point. Back in July, Redmond piped out preview versions of OWA and Office 365, focusing on adding tablet-friendly touch controls. Feedback from over 750,000 users and Windows 8's impending deadline helped shaped today's release, readying it for Microsoft's latest operating system, IE10 and iOS 6. A pair of posts on the Office Web Apps Blog detail the new face of Office, including an improved authoring experience, better support for multi-user collaboration, faster performance and more. Read it for yourself at the source link below, or just log into Skydrive and get to work.

Filed under: , , ,

New Office Web Apps get finalized for SkyDrive, Outlook originally appeared on Engadget on Tue, 23 Oct 2012 01:59:00 EDT. Please see our terms for use of feeds.

Permalink   |   | Email this | Comments

Source: http://www.engadget.com/2012/10/23/new-office-web-apps-go-live-on-skydrive-outlook/

julianne hough brandy calvin johnson calvin johnson michael pineda charles taylor bruins

Army opens Manpack and Rifleman Radio competitions | Defense ...

Army leaders announced Monday they will open the Rifleman and Manpack Radio competitions Monday with the defense industry eager to tackle a contract that could yield a multi-billion dollar purse as the Army looks to reinvigorate their aging communications architecture.

The Army has listed its Network and communications systems as the service?s top modernization priority. The Pentagon canceled the Joint Tactical Radio System. Army officials, however, look to salvage the Rifleman and Manpack Radio systems that fell under JTRS.

General Dynamics has received an order from the Army for 3,726 Manpacks. Army officials have ordered another 19,327 Rifleman Radios splitting the order between General Dynamics and Thales.

Despite the orders, the Army chose to open the competition to bidders. Army leaders said on the floor at the Association of the U.S. Army that they have not lost faith in either General Dynamics or Thales to build the radios, but its in the best interests of the Army to review as many offers as possible.

Heidi Shyu, the Army?s acquisition chief, has made clear her desire to instill as much competition as possible in order to save money.

The Manpacks have also already run into problems in testing at the White Sands Missile Range where the Army holds the Network Integration Evaluation. Independent Pentagon testers found the Manpacks didn?t hold up in simulated combat conditions. General Dynamics contends the conditions were too extreme with the multitude of radios in the desert causing problems with all radios in the area.

A host of companies are expected to bid to build the two radio systems to include BAE Systems, Harris as well as General Dynamic and Thales. With so few defense contracts up for bid, this one will draw a considerable amount of attention.

Source: http://defensetech.org/2012/10/22/army-opens-manpack-and-rifleman-radio-competitions/

robert kardashian chicago weather forecast narcolepsy narcolepsy weather st louis faceoff kings island

Tuesday, October 23, 2012

BBC faces more fallout on Savile scandal

Britain's Prime Minister David Cameron makes a speech on criminal justice in London, Monday, Oct. 22, 2012. (AP Photo/Matt Dunham-Pool)

Britain's Prime Minister David Cameron makes a speech on criminal justice in London, Monday, Oct. 22, 2012. (AP Photo/Matt Dunham-Pool)

FILE - This is a Dec. 17, 1986 file photo of British disc jockey and BBC TV presenter Jimmy Savile at Madame Tussauds museum in London. The BBC is struggling to contain a crisis sparked by allegations of serial sexual abuse against the late Jimmy Savile, a longtime children's television host. Dozens of women have come forward to say that Savile, who died in October 2011 aged 84, sexually assaulted them when they were as young as 13. London's Metropolitan Police, which is leading a national investigation, says it has identified 40 potential victims. (AP Photo/John Redman)

(AP) ? The BBC faced growing fallout Monday over sexual abuse allegations against a popular children's TV entertainer, as Prime Minister David Cameron accused the broadcaster of changing its story about why it killed a news segment on the accusations.

The powerful broadcaster tried to stem the damage, saying in a statement that a top editor had stepped down from its BBC Newsnight program after he was found to have given incomplete, inaccurate explanations for the decision to keep an investigation of the late Jimmy Savile from being broadcast in December.

The scandal is one of the worst to rock the BBC, long a key player in British public life and often cited as one of the most trusted sources of accurate, unbiased information.

"The BBC is a public service broadcaster that depends on the public trust, and anything that suggests it hasn't been truthful undermines that trust," Conservative Party lawmaker Rob Wilson told The Associated Press. "That's why this is such an important issue for them."

Police are investigating accusations against Savile and say there may be more than 200 potential victims of the entertainer, the longtime host of the BBC's "Top of the Pops" and "Jim'll Fix It," recognized for his garish track suits and platinum hair.

The BBC's tough statement about editor Peter Rippon deepened the suspicion that there had been a cover-up. It is suspected of pulling the Newsnight segment because of its harsh portrayal of Savile, who was hailed as a popular fixture in children's TV when he died at 84 last year.

Wilson said the BBC has tried to evade responsibility for its long tolerance of Savile.

"They were sidestepping the story, hoping it would go away," he said. "The BBC was saying the cultural issues that led to this were in the past, but when we saw BBC looking at the Jimmy Savile issue and finding out uncomfortable things, they appeared to want to cover it up."

The BBC's backtracking prompted unusual criticism from the prime minister.

"The nation is appalled, we are all appalled by the allegations of what Jimmy Savile did and they seem to get worse by the day," Cameron said, accusing the BBC of changing its story about why it decided not to broadcast the piece.

Tim Burt, a managing partner of the Stockwell Communications crisis management firm, said BBC faces a major blow to its reputation at a time when it is entering delicate negotiations with the government about the terms of its charter.

??????????? "So to have a civil war inside on a matter of editorial judgment and the handling of potentially criminal investigations could not have come at worse time," he said.

??????????? The BBC plans to air its own investigation into its actions on a show Monday night.

Rippon is the first BBC figure directly blamed for the broadcaster's failure to properly report on abuse claims. He is stepping down immediately for the duration of the investigation.

The BBC Trust, the corporation's governing body, conceded there had been "inaccuracies in the BBC's own description of what happened in relation to the Newsnight investigation."

The BBC says Rippon's explanation of his decision in a blog post earlier was "inaccurate or incomplete in some respects."

BBC is publicly funded through its license fees and various commercial enterprises; it enjoys a large degree of independence from government but is subject to legislation passed by Parliament.

In a statement released Monday, the BBC cited three problems with Rippon's initial statements about why the segment was not aired.

The BBC said Rippon's blog indicated that Newsnight staff had no evidence against the BBC when in fact there were allegations that some of the abuse happened on BBC premises.

It also faulted Rippon for saying that all the abuse victims interviewed by the program had told police about the abuse, when in some cases the women had not done so, meaning that police were "not aware of all the allegations" against Savile.

In addition, BBC said Rippon had indicated that there was no evidence that anyone working at the Duncroft school was aware of allegations that Savile had abused girls there, when in fact there were indications that "some of the Duncroft staff knew or may have known about the abuse."

_______

Associated Press writers David Stringer and Robert Barr in London contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-10-22-Britain-Jimmy%20Savile/id-0f8c9dd0bfd5451fa82d65f78ef9ea73

tony blankley charles barkley beyonce troy polamalu james harrison james harrison falcons